3D printing has gained enormous attention from researchers due to its unique features. The flexibility of the design, minimum waste generation, optimum resource utilization, rapid prototyping, precision of print dimensions, ease of manufacturing, and print-on-demand are some of the key advantages of 3D printing. With the advancement and increasing role of nanotechnology in 3D printing, the outreach is expanding from common applications to biomedical products. This chapter highlights the recent advancements in 3D printing technologies and the emerging role of nanotechnology to further synergize the properties of 3D-printed materials across various end products. Furthermore, various materials used for 3D printing have been discussed with their advantages and challenges for specific applications.