Learning Accurate Rigid Registration for Longitudinal Brain MRI from Synthetic DataShow others and affiliations
2025 (English)In: ISBI 2025 - 2025 IEEE 22nd International Symposium on Biomedical Imaging, Proceedings, Institute of Electrical and Electronics Engineers (IEEE) , 2025Conference paper, Published paper (Refereed)
Abstract [en]
Rigid registration aims to determine the translations and rotations necessary to align features in a pair of images. While recent machine learning methods have become state-of-the-art for linear and deformable registration across subjects, they have demonstrated limitations when applied to longitudinal (within-subject) registration, where achieving precise alignment is critical. Building on an existing framework for anatomy-aware, acquisition-agnostic affine registration, we propose a model optimized for longitudinal, rigid brain registration. By training the model with synthetic within-subject pairs augmented with rigid and subtle nonlinear transforms, the model estimates more accurate rigid transforms than previous cross-subject networks and performs robustly on longitudinal registration pairs within and across magnetic resonance imaging (MRI) contrasts.
Place, publisher, year, edition, pages
Institute of Electrical and Electronics Engineers (IEEE) , 2025.
Keywords [en]
deep learning, longitudinal analysis, neuroimaging, rigid image registration
National Category
Medical Imaging Radiology and Medical Imaging
Identifiers
URN: urn:nbn:se:kth:diva-364140DOI: 10.1109/ISBI60581.2025.10980859ISI: 001546451000187Scopus ID: 2-s2.0-105005825114OAI: oai:DiVA.org:kth-364140DiVA, id: diva2:1964095
Conference
22nd IEEE International Symposium on Biomedical Imaging, ISBI 2025, Houston, United States of America, Apr 14 2025 - Apr 17 2025
Note
Part of ISBN 979-8-3315-2052-6
QC 20250609
2025-06-042025-06-042026-05-29Bibliographically approved