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Domain-Adversarial Pretrained Encoder for ECG-Based Chagas Disease Screening
KTH.
KTH, School of Electrical Engineering and Computer Science (EECS), Intelligent systems, Information Science and Engineering.ORCID iD: 0000-0002-7117-1267
Rutherford Appleton Laboratory, United Kingdom.
KTH, School of Electrical Engineering and Computer Science (EECS), Intelligent systems, Information Science and Engineering.ORCID iD: 0000-0003-2638-6047
2025 (English)In: Computing in Cardiology, CinC 2025, Computing in Cardiology , 2025Conference paper, Published paper (Refereed)
Abstract [en]

Chagas disease (ChD) remains a major health burden in Latin America, and scalable screening tools are required to pre-select high-risk patients for confirmatory testing. Electrocardiograms (ECGs) are widely available, but machine learning models trained on heterogeneous datasets are vulnerable to domain bias. As part of the ‘Detection of Chagas Disease from the ECG: The George B. Moody PhysioNet Challenge 2025’, this paper presents a domain-aware framework using a transformer encoder initialized with released pretrained weights, combined with a four-class reformulation of SaMi-Trop and PTB-XL cohorts and a domain-adversarial head to promote domain-invariant features. In five-fold cross-validation, the model achieved an average challenge score (Recall@5%) of 0.824 (best 0.852, with AUROC/AUPRC of 0.883/0.852). Predicted probabilities remained conservative, avoiding extreme confidence while maintaining strong ranking. Submitted under the team name FjordNet, this model achieved an official test score of 0.173, ranking 31st out of 41 teams. These results demonstrate that the transformer encoder structure with multi-class adversarial training improve local robustness, but domain-aware validation and dataset diversification are necessary for generalizable ChD ECG screening.

Place, publisher, year, edition, pages
Computing in Cardiology , 2025.
National Category
Computer Sciences
Identifiers
URN: urn:nbn:se:kth:diva-376724DOI: 10.22489/CinC.2025.091Scopus ID: 2-s2.0-105028510885OAI: oai:DiVA.org:kth-376724DiVA, id: diva2:2039548
Conference
52nd International Computing in Cardiology, CinC 2025, Sao Paulo, Brazil, September 14-17, 2025
Note

QC 20260218

Available from: 2026-02-18 Created: 2026-02-18 Last updated: 2026-02-18Bibliographically approved

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Dong, TianzhengBao, XinqiChatterjee, Saikat

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CiteExportLink to record
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  • apa
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Output format
  • html
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  • asciidoc
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